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Image Search Results
Journal: Cerebral Cortex (New York, NY)
Article Title: A Layer-specific Corticofugal Input to the Mouse Superior Colliculus
doi: 10.1093/cercor/bhx161
Figure Lengend Snippet: Areal characterization of cortico-superior-collicular neurons. (a) Epifluorescence images show retrogradely labeled neurons in a series of slices containing the AC. Dashed yellow lines indicate areal boundaries between the dorsal, primary, and ventral AC. (b) Schematic from the Allen Institute for Brain Science coronal mouse atlas which was used to reference the boundaries between the cortical areas. (c) Continuing in series from panel a. (d) Continuing in series from panel b.
Article Snippet: Dashed yellow lines indicate areal boundaries between the dorsal, primary, and ventral AC. ( b ) Schematic from the
Techniques: Labeling
Journal: Nature Communications
Article Title: Cooperative integration of spatially resolved multi-omics data with COSMOS
doi: 10.1038/s41467-024-55204-y
Figure Lengend Snippet: a Annotation of P56 mouse brain coronal sections from the Allen Brain Atlas. b Manual annotation of tissue from P22 mouse brain coronal sections in Zhang et al., overlaid on the image from a . c Comparison of domain segmentation results from five algorithms. Note that SpaMultiVAE was excluded as it is not designed for ATAC-RNA multi-omics data analysis. d Distribution of modality weights for RNA and ATAC in COSMOS analysis. e UMAP visualizations of integrated embeddings produced by SpatialGlue and COSMOS. f Pseudo-spatiotemporal maps (pSM) generated by SpatialGlue and COSMOS. ( g) Gene Ontology Biological Process (GOBP) analysis of genes associated with pseudo-time. h Gene expression profiles for the top 15 positive and 15 negative pSM-associated genes. i Spatial mapping of gene expressions for brain development genes negatively ( Nexn, Bcl11b, Mbp ) and positively ( Nfix, Mef2c, Cux2 ) correlated with pseudo-time, as identified by COSMOS. The full names of the abbreviations of brain regions are: nucleus accumbens (ACB), caudoputamen (CP), lateral ventricle (VL), genu of corpus callosum (ccg) and anterior commissure olfactory limb (aco). Source data are provided as a Source Data file.
Article Snippet: The reference of mouse brain ATAC-RNA data is obtained from a
Techniques: Comparison, Biomarker Discovery, Produced, Generated, Gene Expression